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Dr. Andy Galpin

Appeared on:Huberman Lab
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โ€œThere's about nine different adaptations you can get from exercise... some of those cross over and some are actually a little bit contrary to the other ones.โ€

โ€” Andy Galpin
APR 2, 2026Scicomm Media

Essentials: How to Build Strength, Muscle Size & Endurance | Dr. Andy Galpin

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    Exercise yields nine distinct adaptations - physical training can be dialed into specific goals like power, hypertrophy, or endurance, though over-prioritizing one can sometimes hinder progress in another.

    โ€œThere's about nine different adaptations you can get from exercise... some of those cross over and some are actually a little bit contrary to the other ones.โ€

    โ€” Andy Galpin
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    Progressive overload is the engine of adaptation - physiological change only occurs as a byproduct of stress, requiring intentional increases in weight, volume, or complexity over time.

    โ€œIf you want to continue to improve, you have to have some method of overload. Adaptation physiologically happens as a byproduct of stress.โ€

    โ€” Andy Galpin
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    Muscle soreness is a poor indicator of workout quality - chasing extreme soreness is counterproductive as it forces skipped sessions and lowers the total training frequency necessary for long-term gains.

    โ€œSoreness is a terrible proxy for exercise quality. It's a really bad way to estimate whether it was a good or a bad workout.โ€

    โ€” Andy Galpin